Jayasri Nanduri, Ph.D.
Research Professor Department of Medicine
Biographical Info
Research Interest
My research is focused on investigating the effects of chronic intermittent hypoxia: cellular and molecular mechanisms underlying autonomic responses in a rodent model. The main areas of my research are 1) Significance of hypoxia inducible factors in IH-induced oxidative stress, 2) Epigenetic mechanisms regulating IH-induced oxidative stress and 3) effects of oxidative stress on insulin metabolism and ion channels all of which play a critical role in the pathogenesis of cardio-respiratory complications associated with sleep apnea.
Featured Publications
- Immunohistochemistry of the Carotid Body
- DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity
- Epigenetic changes by DNA methylation in chronic and intermittent hypoxia
- Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia
- Epigenetic Regulation of Carotid Body Oxygen Sensing: Clinical Implications
- Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome
For a complete list of publications click here:
Training
- Ph.D., 1982, Andhra University, Physical Chemistry
- M.S., 1977, Andhra University, Physical Chemistry
Categories: Senior Fellow
