Nanduri R. Prabhakar

Francisco Bezanilla

Aaron Fox

Peggy Mason

Anxiolytic Treatment Impairs Helping Behavior in Rats

Pro-social behavior in rats is modulated by social experience

Empathy and pro-social behavior in rats

Caffeine accelerates recovery from general anesthesia

With a little help from our friends: how the brain processes empathy

Opioids disrupt pro-nociceptive modulation mediated by raphe magnus

Two negatives make a positive: telencephalic-mediated analgesia

Daniel McGehee

Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum

Nicotinic modulation of descending pain control circuitry

Sensitizing exposure to amphetamine increases AMPA receptor phosphorylation without increasing cell surface expression in the rat nucleus accumbens

Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum

Ethanol-Induced Motor Impairment Mediated by Inhibition of α7 Nicotinic Receptors

Chronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency

Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia

Striatal cholinergic interneuron regulation and circuit effects

Cyclic AMP and afferent activity govern bidirectional synaptic plasticity in striatopallidal neurons

Nicotinic receptors regulate the dynamic range of dopamine release in vivo

Neuronal nicotinic receptors as analgesic targets: it’s a winding road

Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitises locomotor responding to the drug

A role for dopamine-mediated learning in the pathophysiology and treatment of Parkinson’s disease

Julian Solway

Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma

DNA methylation in lung cells is associated with asthma endotypes and genetic risk

An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma

Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways

Future Research Directions in Asthma. An NHLBI Working Group Report

Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways

Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis

High-throughput screening for modulators of cellular contractile force

Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells

Genome-wide interrogation of longitudinal FEV1 in children with asthma

MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle

A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes

Airway contractility in the precision-cut lung slice after cryopreservation

Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial

Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation

Gata5 deficiency causes airway constrictor hyperresponsiveness in mice

E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation

Airway smooth muscle: a potential target for asthma therapy

Emerging targets for novel therapy of asthma

The sharing partnership for innovative research in translation (SPIRiT) consortium: a model for collaboration across CTSA sites

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633092/pdf/CTS-6-085.pdf

Maternal asthma and microRNA regulation of soluble HLA-G in the airway

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779062/pdf/nihms505998.pdf

Airway smooth muscle in the pathophysiology and treatment of asthma

https://www.physiology.org/doi/pdf/10.1152/japplphysiol.00950.2012

Francis Alenghat

Protein Mimetic and Anticancer Properties of Monocyte-Targeting Peptide Amphiphile Micelles

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749269/pdf/nihms913627.pdf

The Prevalence of Atherosclerosis in Those with Inflammatory Connective Tissue Disease by Race, Age, and Traditional Risk Factors

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740809/pdf/srep20303.pdf

Monocyte-targeting supramolecular micellar assemblies: a molecular diagnostic tool for atherosclerosis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336846/pdf/nihms-632144.pdf

Membrane protein dynamics and functional implications in mammalian cells

Nickolai Dulin

P311 Promotes Lung Fibrosis via Stimulation of TGF-β1, 2 and 3 Translation


https://www.atsjournals.org/doi/pdf/10.1165/rcmb.2018-0028OC

Fibroblast growth factor 2 decreases bleomycin-induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation

https://onlinelibrary.wiley.com/doi/epdf/10.1002/path.5106

Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines

https://www.fasebj.org/doi/pdf/10.1096/fj.201700555R

Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis

https://www.atsjournals.org/doi/abs/10.1165/rcmb.2017-0186OC?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed#readcube-epdf

Na+,K+-ATPase as a Target for Treatment of Tissue Fibrosis

http://www.eurekaselect.com/153419/article

Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179089/pdf/pone.0168363.pdf

Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production*

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207151/pdf/zbc27239.pdf

SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage

https://www.physiology.org/doi/pdf/10.1152/ajplung.00188.2016

Skeletal muscle as an endocrine organ: Role of [Na+]i/[K+]i-mediated excitation-transcription coupling

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012537/pdf/main.pdf

Regulation of myofibroblast differentiation by cardiac glycosides

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867347/?report=printable

NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477834/pdf/main.pdf

Mechano-Sensitive PPAP2B Regulates Endothelial Responses to Athero-Relevant Hemodynamic Forces

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522239/pdf/nihms-696698.pdf

Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392778/pdf/12931_2015_Article_206.pdf

Organizer regions in marine colonial hydrozoans

https://ac.els-cdn.com/S0944200615000148/1-s2.0-S0944200615000148-main.pdf?_tid=671e5eb5-764d-48e4-bd12-851fad554ab2&acdnat=1540487709_daa9fe8f7d543a8e116bd1abced29ebd

Antifibrotic Effects of Noscapine through Activation of Prostaglandin E2 Receptors and Protein Kinase A*

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953264/pdf/zbc7505.pdf

Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680759/?report=printable

RGS expression in cancer: oncomining the cancer microarray data

https://www.tandfonline.com/doi/full/10.3109/10799893.2013.773450?scroll=top&needAccess=true

Yun Fang

Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322949/pdf/nihms629779.pdf

Hypercholesterolemia-Induced Loss of Flow-Induced Vasodilation and Lesion Formation in Apolipoprotein E-Deficient Mice Critically Depend on Inwardly Rectifying K+ Channels.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866319/pdf/JAH3-7-e007430.pdf

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495571/pdf/elife-25217.pdf

The Runt of the Litter-Stronger than We Thought?

https://www.atsjournals.org/doi/abs/10.1165/rcmb.2017-0059ED?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed#readcube-epdf

Letter by Wu et al Regarding Article, “Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites”

https://www.ahajournals.org/doi/pdf/10.1161/ATVBAHA.117.310335

NOTCH1 is a mechanosensor in adult arteries

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696341/pdf/41467_2017_Article_1741.pdf

Protein Mimetic and Anticancer Properties of Monocyte-Targeting Peptide Amphiphile Micelles

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749269/pdf/nihms913627.pdf

Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation.

https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.117.312130

Monocyte-targeting supramolecular micellar assemblies: a molecular diagnostic tool for atherosclerosis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336846/pdf/nihms-632144.pdf

Dual Functions of Crystallization Control and Defect Passivation Enabled by Sulfonic Zwitterions for Stable and Efficient Perovskite Solar Cells

https://onlinelibrary.wiley.com/doi/epdf/10.1002/adma.201803428

Experimental Lung Injury Reduces Krüppel-like Factor 2 to Increase Endothelial Permeability via Regulation of RAPGEF3-Rac1 Signaling

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363977/pdf/rccm.201604-0668OC.pdf

Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522239/pdf/nihms-696698.pdf

Robert Guzy

    • Fibroblast growth factor 2 decreases bleomycin‐induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation

https://onlinelibrary.wiley.com/doi/epdf/10.1002/path.5106

Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis

https://www.atsjournals.org/doi/full/10.1165/rcmb.2017-0186OC?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed#readcube-epdf

Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565396/pdf/nihms892936.pdf

Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481550/pdf/zbc10364.pdf

Comprehensive Care of the Lung Transplant Patient

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026268/pdf/main.pdf

Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370255/pdf/rcmb.2014-0184OC.pdf

YKL-40 in Pediatric Asthma, MUC5B Promoter Polymorphism in Idiopathic Pulmonary Fibrosis, and Esmolol in Septic Shock

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446197/pdf/rccm.201312-2253RR.pdf

Superoxide Generated at Mitochondrial Complex III Triggers Acute Responses to Hypoxia in the Pulmonary Circulation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603595/pdf/AJRCCM1874424.pdf

Robert Hamanaka

Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis

https://www.atsjournals.org/doi/full/10.1165/rcmb.2017-0186OC?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed#readcube-epdf

Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207151/pdf/zbc27239.pdf

Experimental Lung Injury Reduces Krüppel-like Factor 2 to Increase Endothelial Permeability via Regulation of RAPGEF3–Rac1 Signaling

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363977/pdf/rccm.201604-0668OC.pdf

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495571/pdf/elife-25217.pdf

Regulation of myofibroblast differentiation by cardiac glycosides

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867347/?report=printable

Letter by Wu et al Regarding Article, “Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites”

https://www.ahajournals.org/doi/pdf/10.1161/ATVBAHA.117.310335

Prolonged Exposures to Intermittent Hypoxia Promote Visceral White Adipose Tissue Inflammation in a Murine Model of Severe Sleep Apnea: Effect of Normoxic Recovery

https://watermark.silverchair.com/zsw074.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAjEwggItBgkqhkiG9w0BBwagggIeMIICGgIBADCCAhMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMEGdD0Li2QyiY4DNiAgEQgIIB5N979Duvs26jgRt_3bpUNPPha5yi0xvTdJtXVtz7y8o2cZD5vtdcgZh5ra4nrK78Y8FAmlWDLRiZEB7OjPGnYjcaRtDUv51Wc-JHNeJ-XcbEHZz9NAzUzaVai_kKQ4yrtul6TIlumYt5vmdK41hPJ5F5Z9SLjb8uqZP8r8eAT6FmEwjWs7i3CRP_C8FNF-aadfXWN5eVnk4qTF_7Cz_uBNaQcmuSrwJRT5dDsrhXgNkEQI-NpJp_J859-m5ox_7AVsAQSiuSce432hfVhk-y322QHmWGdkfhhQGKw8w6bCtCAJuKV-GkmMe1o2UTtqpJY5VJ6Zssz53t-7JvBiruWqSFiGbuLhSIJQRRrJD_pQe3pwa4r62LqnqKDEfyYP3s47MYDq7QDmiynJHmId4AHkbUdZ1nI7T-8FyoXeu3mPv1iwNitDIokRYeBVnGxVRxcImBoSo_KjuKvn_mxbqDZrL7puYcjN-ofpC4Xy70e46DAd6C5nQhjFOxYp539BlH5qZBj_X3PXCyYvI9fvLd1Q7zRvcJsPbf5eSUP8yZ5_MgRL1Biyij1nO7Acp8h3_yJTaamUtpdqXdTXV8Npz3PQgrabY4UoaVE7d9ZKbJYV6cIoAff0bXZPfrz66oKWuEJXg_qqI

Impaired Clearance of Influenza A Virus in Obese, Leptin Receptor Deficient Mice Is Independent of Leptin Signaling in the Lung Epithelium and Macrophages

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169489/pdf/pone.0108138.pdf

Mitochondrial metabolism as a regulator of keratinocyte differentiation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891634/pdf/cl-3-e25456.pdf

The mitochondrial respiratory chain is required for organismal adaptation to hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838509/pdf/nihms771121.pdf

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017376/pdf/nihms573248.pdf

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017650/pdf/elife02242.pdf

PFKFB3, a direct target of p63, is required for proliferation and inhibits differentiation in epidermal keratinocytes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441935/pdf/nihms859505.pdf

The NIEHS TaRGET II Consortium and environmental epigenomics

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991835/pdf/nihms971445.pdf

Inhalational exposure to particulate matter air pollution alters thecomposition of the gut microbiome

https://reader.elsevier.com/reader/sd/pii/S0269749117351552?token=328D715E18E2EDA7DE9E3965D7ACB66F16590000B7CEF9D890FDD61CABFAFD9C9F24C16ECAF14A74E8BED7EB90B78130

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis

https://ac.els-cdn.com/S1550413118305862/1-s2.0-S1550413118305862-main.pdf?_tid=c3f7a9e2-b357-4fc0-b921-9cfb23fb3a13&acdnat=1542129475_5be94e3527f787de765c7b39128bfdf2

Alveolar Epithelial Cells Burn Fat to Survive Acute Lung Injury

https://www.atsjournals.org/doi/pdf/10.1165/rcmb.2018-0300ED

Willard Sharp

Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608301/pdf/pone.0185046.pdf

Inhibition of the Mitochondrial Fission Protein Drp1 Improves Survival in a Murine Cardiac Arrest Model

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342059/pdf/nihms665710.pdf

PGC1α-mediated Mitofusin-2 Deficiency in Female Rats and Humans with Pulmonary Arterial Hypertension

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707374/pdf/rccm.201209-1687OC.pdf

Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390778/pdf/nihms857867.pdf

Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868827/?report=printable

The emergency cardiac arrest response team (eCART): A novel strategy for improving therapeutic hypothermia utilization following out-of-hospital cardiac arrest

https://ac.els-cdn.com/S0300957214007850/1-s2.0-S0300957214007850-main.pdf?_tid=1ccf9afe-dfd5-4ef9-9357-279cd6fee0a5&acdnat=1542131439_824ffabcd326d12ea6993e2948abf325

Mitochondrial Dynamics in Cardiovascular Disease: Fission and fusion foretell form and function

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338002/

Role of Dynamin Related Protein 1 (Drp1)-Mediated Mitochondrial Fission in Oxygen-Sensing and Constriction of the Ductus Arteriosus

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957065/pdf/nihms-560901.pdf

Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470953/pdf/oncotarget-08-34082.pdf

Dynamin-Related Protein 1 as a therapeutic target in cardiac arrest

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334717/pdf/nihms662396.pdf

EM:RAP Commentaries in the Annals of Emergency Medicine: Peer Review and Financial Disclosure Needed

https://ac.els-cdn.com/S0196064415002139/1-s2.0-S0196064415002139-main.pdf?_tid=0bd8b9f6-0644-431b-89d4-243fe4762f4c&acdnat=1542131658_7f1daad54c5543756f25497965c87256

The Crisis in the Emergency Medicine Physician Scientist Workforce

https://onlinelibrary.wiley.com/doi/epdf/10.1111/acem.12635

Esra Tasali

Shared Genetic Control of Brain Activity During Sleep and Insulin Secretion: A Laboratory-Based Family Study

http://diabetes.diabetesjournals.org/content/67/1/155.full-text.pdf

Composition of two‐week change in body weight under unrestricted free‐living conditions

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506524/pdf/PHY2-5-e13336.pdf

Effects of Insufficient Sleep on Pituitary–Adrenocortical Response to CRH Stimulation in Healthy Men

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075556/pdf/zsx064.pdf

Continuous Positive Airway Pressure for Improving Glycemic Control in Type 2 Diabetes: Where Do We Stand?

https://www.atsjournals.org/doi/full/10.1164/rccm.201604-0698ED?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed#readcube-epdf

Postprandial Metabolism of Macronutrients and Cardiometabolic Risk: Recent Developments, Emerging Concepts, and Future Directions1,2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785471/pdf/an010397.pdf

Two Nights of Recovery Sleep Reverses the Effects of Short-term Sleep Restriction on Diabetes Risk

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764036/pdf/dc152214.pdf

Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763355/pdf/aasm.39.3.653.pdf

Elevated ghrelin predicts food intake during experimental sleep restriction

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688118/pdf/nihms717668.pdf

Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult: Methodology and Discussion

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513271/pdf/jcsm.11.8.931.pdf

Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434546/pdf/aasm.38.6.843.pdf

Eight Hours of Nightly Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea Improves Glucose Metabolism in Patients with Prediabetes. A Randomized Controlled Trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511421/pdf/rccm.201408-1564OC.pdf

Sleep restriction increases free fatty acids in healthy men

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358810/pdf/nihms668342.pdf

Circadian Rhythm of Circulating Levels of the Endocannabinoid 2-Arachidonoylglycerol

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399498/?report=printable

The Effects of Extended Bedtimes on Sleep Duration and Food Desire in Overweight Young Adults: A Home-Based Intervention

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112413/pdf/nihms603258.pdf

Adverse Effects of Two Nights of Sleep Restriction on the Hypothalamic-Pituitary-Adrenal Axis in Healthy Men

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121029/?report=printable

New frontiers in obstructive sleep apnoea

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348094/pdf/nihms664846.pdf

Benoit Roux

Molecular Dynamics of Ion Conduction through the Selectivity Filter of the NaVAb Sodium Channel

https://pubs.acs.org/doi/ipdf/10.1021/acs.jpcb.8b09678

Reproducibility of Free Energy Calculations across Different Molecular Simulation Software Packages


https://pubs.acs.org/doi/10.1021/acs.jctc.8b00544

1H, 15N, and 13C resonance assignments of the intrinsically disordered SH4 and Unique domains of Hck

https://link.springer.com/content/pdf/10.1007%2Fs12104-018-9854-z.pdf

Reduced Free Energy Perturbation/Hamiltonian Replica Exchange Molecular Dynamics Method with Unbiased Alchemical Thermodynamic Axis

https://pubs.acs.org/doi/ipdf/10.1021/acs.jpcb.8b03277

Corrigendum to “A Catalytically-Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation.” J. Mol. Biol. 430(6) (Mar 16 2018), 881–889

https://reader.elsevier.com/reader/sd/pii/S0022283618310337?token=596470FD293644FDD940767370F64F814C835CCAF538696CBA9741029F90BCDE834B0EF2A0F525892E23B6B8A196EF45

A generalized linear response framework for expanded ensemble and replica exchange simulations

https://aip.scitation.org/doi/pdf/10.1063/1.5027494?class=pdf

Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel

http://jgp.rupress.org/content/150/10/1408.long

Classical Drude Polarizable Force Field Model for Methyl Phosphate and Its Interactions with Mg2+

https://pubs.acs.org/doi/ipdf/10.1021/acs.jpca.8b04418

Combining the polarizable Drude force field with a continuum electrostatic Poisson–Boltzmann implicit solvation model

https://onlinelibrary.wiley.com/doi/epdf/10.1002/jcc.25345

Optimized Lennard-Jones Parameters for Drug-Like Small Molecules

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997559/pdf/nihms963625.pdf

Polarizable Force Field for Molecular Ions Based on the Classical Drude Oscillator

https://pubs.acs.org/doi/ipdf/10.1021/acs.jcim.8b00132

Predicting the Conformational Variability of Abl Tyrosine Kinase using Molecular Dynamics Simulations and Markov State Models

https://pubs.acs.org/doi/ipdf/10.1021/acs.jctc.7b01170

A Catalytically Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation

https://reader.elsevier.com/reader/sd/pii/S0022283618300457?token=4D4719F164DDE46088D17FDECA12680DE05B088088CA22814FDB6D7007CDFF88D4B713E165A2FDDDF7299BCFE0DB162F

Enhanced configurational sampling with hybrid non-equilibrium molecular dynamics–Monte Carlo propagator

https://aip.scitation.org/doi/pdf/10.1063/1.5004154?class=pdf

Water Flux Induced Reorientation of Liquid Crystals

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746861/pdf/oc7b00495.pdf

Graph–Theoretic Analysis of Monomethyl Phosphate Clustering in Ionic Solutions

https://pubs.acs.org/doi/ipdf/10.1021/acs.jpcb.7b10730

Constant-pH Molecular Dynamics Simulations for Large Biomolecular Systems

https://pubs.acs.org/doi/ipdf/10.1021/acs.jctc.7b00875

Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651753/pdf/pnas.201706983.pdf

New Coarse Variables for the Accurate Determination of Standard Binding Free Energies

https://pubs.acs.org/doi/ipdf/10.1021/acs.jctc.7b00791

Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584448/pdf/pnas.201707547.pdf

Machine Learning Force Field Parameters from Ab Initio Data

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931379/pdf/nihms960350.pdf

Drude Polarizable Force Field for Molecular Dynamics Simulations of Saturated and Unsaturated Zwitterionic Lipids

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595662/

Ion channels and ion selectivity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544903/

Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544906/

Tyrosine Kinase Activation and Conformational Flexibility: Lessons from Src-Family Tyrosine Kinases

https://pubs.acs.org/doi/ipdf/10.1021/acs.accounts.7b00012

Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507063/

Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338507/pdf/pnas.201609579.pdf

Equivalence of M- and P-Summation in Calculations of Ionic Solvation Free Energies

https://pubs.acs.org/doi/ipdf/10.1021/acs.jpca.6b12691

Conformational Transitions and Alternating-Access Mechanism in the Sarcoplasmic Reticulum Calcium Pump

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467534/pdf/nihms843858.pdf

CHARMM-GUI 10 years for biomolecular modeling and simulation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403596/pdf/nihms842647.pdf

The Activation of c-Src Tyrosine Kinase: Conformational Transition Pathway and Free Energy Landscape

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398919/pdf/nihms827682.pdf

Atomic mutagenesis in ion channels with engineered stoichiometry

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092047/pdf/elife-18976.pdf

Efficiency in nonequilibrium molecular dynamics Monte Carlo simulations

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055532/pdf/JCPSA6-000145-134109_1.pdf

Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544905/pdf/nihms884237.pdf

Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052707/pdf/ncomms12753.pdf

The selectivity of the Na(+)/K(+)-pump is controlled by binding site protonation and self-correcting occlusion

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026471/pdf/elife-16616.pdf

Transition path theory analysis of c-Src kinase activation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995974/pdf/pnas.201602790.pdf

Leveraging the Information from Markov State Models To Improve the Convergence of Umbrella Sampling Simulations

https://pubs.acs.org/doi/ipdf/10.1021/acs.jpcb.6b05125

Multiple Time-Step Dual-Hamiltonian Hybrid Molecular Dynamics – Monte Carlo Canonical Propagation Algorithm

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946962/pdf/nihms-798443.pdf

Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939264/pdf/nihms798027.pdf

An Empirical Polarizable Force Field Based on the Classical Drude Oscillator Model: Development History and Recent Applications

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865892/pdf/cr5b00505.pdf

Enhanced Sampling of an Atomic Model with Hybrid Nonequilibrium Molecular Dynamics-Monte Carlo Simulations Guided by a Coarse-Grained Model

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894282/pdf/ct5b00372.pdf

Efficient Determination of Free Energy Landscapes in Multiple Dimensions from Biased Umbrella Sampling Simulations Using Linear Regression

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894281/pdf/ct501130r.pdf

Efficient Determination of Relative Entropy Using Combined Temperature and Hamiltonian Replica-Exchange Molecular Dynamics

https://pubs.acs.org/doi/ipdf/10.1021/ct501034w

Quantum effects in cation interactions with first and second coordination shell ligands in metalloproteins

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827603/pdf/ct5b00524.pdf

Structural Refinement of Proteins by Restrained Molecular Dynamics Simulations with Non-interacting Molecular Fragments

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624691/pdf/pcbi.1004368.pdf

Constant-pH Hybrid Nonequilibrium Molecular Dynamics-Monte Carlo Simulation Method

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535364/pdf/ct5b00261.pdf

Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515779/pdf/ncomms8622.pdf

Computational study of the W260A activating mutant of Src tyrosine kinase

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815304/pdf/PRO-25-219.pdf

Implementation of extended Lagrangian dynamics in GROMACS for polarizable simulations using the classical Drude oscillator model

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481176/pdf/nihms684196.pdf

Perspective on computational and structural aspects of kinase discovery from IPK2014

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105597/pdf/nihms-827437.pdf

Simulating the distance distribution between spin-labels attached to proteins

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509421/pdf/jp510745d.pdf

A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457281/pdf/nihms662284.pdf

Generalized Metropolis acceptance criterion for hybrid non-equilibrium molecular dynamics-Monte Carlo simulations

https://aip.scitation.org/doi/pdf/10.1063/1.4904889?class=pdf

Representation of Ion-Protein Interactions Using the Drude Polarizable Force-Field

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516320/pdf/jp510560k.pdf

Computational study of the “DFG-flip” conformational transition in c-Abl and c-Src tyrosine kinases

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315421/pdf/jp511792a.pdf

Insights into the molecular foundations of electrical excitation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544904/pdf/nihms884246.pdf

CHARMM-GUI PDB manipulator for advanced modeling and simulations of proteins containing nonstandard residues

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739825/pdf/nihms754424.pdf

Conformational cycle and ion-coupling mechanism of the Na+/hydantoin transporter Mhp1

http://www.pnas.org/content/pnas/111/41/14752.full.pdf

Recent Advances in Polarizable Force Fields for Macromolecules: Microsecond Simulations of Proteins Using the Classical Drude Oscillator Model

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167036/pdf/jz501315h.pdf

Generalized Metropolis acceptance criterion for hybrid non-equilibrium molecular dynamics-Monte Carlo simulations

https://aip.scitation.org/doi/pdf/10.1063/1.4904889?class=pdf

Computational analysis of the binding specificity of Gleevec to Abl, c-Kit, Lck, and c-Src tyrosine kinases

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026022/pdf/nihms526359.pdf

Explaining why Gleevec is a specific and potent inhibitor of Abl kinase

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562763/pdf/pnas.201214330.pdf

Locking the Active Conformation of c-Src Kinase through the Phosphorylation of the Activation Loop

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947352/pdf/nihms534289.pdf

Activation pathway of Src kinase reveals intermediate states as novel targets for drug design

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465921/pdf/nihms566211.pdf

AUTOMATED FORCE FIELD PARAMETERIZATION FOR NON-POLARIZABLE AND POLARIZABLE ATOMIC MODELS BASED ON AB INITIO TARGET DATA

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819940/pdf/nihms-510083.pdf

An Overview of Electrostatic Free Energy Computations for Solutions and Proteins

https://pubs.acs.org/doi/ipdf/10.1021/ct500195p

Generalized Scalable Multiple Copy Algorithms for Molecular Dynamics Simulations in NAMD

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059768/pdf/nihms582999.pdf

A Polarizable Force Field of Dipalmitoylphosphatidylcholine based on the Classical Drude Model for Molecular Dynamics Simulations of Lipids

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799809/pdf/nihms511433.pdf

Self-Learning Adaptive Umbrella Sampling Method for the Determination of Free Energy Landscapes in Multiple Dimensions

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694627/pdf/nihms460844.pdf

A structural study of ion permeation in OmpF porin from anomalous X-ray diffraction and molecular dynamics simulations

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868647/pdf/nihms-535833.pdf

William N. Green

A novel function for the ER retention signals in the C-terminus of kainate receptor subunit, GluK5

https://ac.els-cdn.com/S0167488918304506/1-s2.0-S0167488918304506-main.pdf?_tid=6e177bef-eec2-496b-bc36-1463831636b8&acdnat=1542822252_8e1ab47baa3b4ec09ca4d6bf25021d35

Frontiers in Neurochemistry

https://onlinelibrary.wiley.com/doi/epdf/10.1002/cphc.201800361

Development of fluorescence imaging probes for nicotinic acetylcholine α4β2∗ receptors

https://reader.elsevier.com/reader/sd/pii/S0960894X17312118?token=7E6E5B6896D1C23DA725AC1B5669E337FCCD58F57B713E0EE1EC1CAF6939F1B964DB5CF4C1B4E6805789F6EDEFFC91AD

Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779237/pdf/elife-27744.pdf

Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546804/pdf/elife-25651.pdf

S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264640/pdf/srep41141.pdf

Palmitoylation regulates glutamate receptor distributions in postsynaptic densities through control of PSD95 conformation and orientation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206547/pdf/pnas.201612963.pdf

Synaptic activity regulates AMPA receptor trafficking through different recycling pathways

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451724/pdf/elife06878.pdf

Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877647/pdf/IJCB2013-560421.pdf

CASK Regulates SAP97 Conformation and Its Interactions with AMPA and NMDA Receptors

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713737/pdf/zns12067.pdf

Palmitoylation of Superoxide Dismutase 1 (SOD1) Is Increased for Familial Amyotrophic Lateral Sclerosis-linked SOD1 Mutants*

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724620/pdf/zbc21606.pdf

Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitizes locomotor responding to the drug

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604051/pdf/nihms425428.pdf

Dorothy A. Hanck

Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675820/pdf/main.pdf

Deborah J. Nelson

Support of bone mineral deposition by regulation of pH

https://www.physiology.org/doi/pdf/10.1152/ajpcell.00056.2018

Osteoblast Differentiation and Bone Matrix Formation In Vivo and In Vitro

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467150/pdf/ten.teb.2016.0454.pdf

TRPC6 channel translocation into phagosomal membrane augments phagosomal function

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664321/pdf/pnas.201518966.pdf

Chloride–hydrogen antiporters ClC-3 and ClC-5 drive osteoblast mineralization and regulate fine-structure bone patterning in vitro

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673636/pdf/phy20003-e12607.pdf

Claudin-2-dependent paracellular channels are dynamically gated

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755754/pdf/elife-09906.pdf

HEK‐293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl− transport

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270233/pdf/phy2-2-e12158.pdf

Quantifying Insulin Sensitivity and Entero-Insular Responsiveness to Hyper- and Hypoglycemia in Ferrets

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940889/pdf/pone.0090519.pdf

CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral–CA1 synapses

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591711/pdf/tjp0591-1001.pdf

Eduardo Perozo

Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel

http://jgp.rupress.org/content/jgp/150/10/1408.full.pdf

Never at rest: insights into the conformational dynamics of ion channels from cryo‐electron microscopy


https://physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/JP274888

Structural Dynamics of the MscL C-terminal Domain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722894/pdf/41598_2017_Article_17396.pdf

The gating cycle of a K+ channel at atomic resolution

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711375/pdf/elife-28032.pdf

Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651753/pdf/pnas.201706983.pdf

Towards a Structural View of Drug Binding to hERG K+ Channels

https://reader.elsevier.com/reader/sd/pii/S0165614717301256?token=975A95FEB76522C68C4CCD6FCC5166736F3E07CDEADE2604AF050BD194F18F1013C1EAD63246AB68170C04C683B4D8A1

Probing the effects of gating on the ion occupancy of the K+ channel selectivity filter using 2D IR spectroscopy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544906/pdf/nihms884238.pdf

Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544905/pdf/nihms884237.pdf

From nanodiscs to isotropic bicelles: a procedure for solution NMR studies of detergent sensitive integral membrane proteins

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064851/pdf/nihms815964.pdf

Toward a structural blueprint for bilayer-mediated channel mechanosensitivity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398584/pdf/kchl-11-02-1224624.pdf

The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917966/pdf/ncomms11984.pdf

Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939264/pdf/nihms798027.pdf

Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break Upon Gating

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752722/pdf/nihms749102.pdf

Conformational chaperones for structural studies of membrane proteins using antibody phage display with nanodiscs

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740257/pdf/nihms745283.pdf

Resting state of the human proton channel dimer in a lipid bilayer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640771/pdf/pnas.201515043.pdf

Biomolecular DNP‐Supported NMR Spectroscopy using Site‐Directed Spin Labeling

https://onlinelibrary.wiley.com/doi/epdf/10.1002/chem.201501376

xMDFF: molecular dynamics flexible fitting of low-resolution X-ray structures

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157446/pdf/d-70-02344.pdf

Molecular Mechanism of Mg2+-dependent gating in CorA

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066822/pdf/nihms574006.pdf

Conformational Dynamics at the Inner Gate of KcsA during Activation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010282/pdf/bi500168u.pdf

A repulsion mechanism explains magnesium permeation and selectivity in CorA

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939898/pdf/pnas.201319054.pdf

Biochemical and Structural Analysis of the Hyperpolarization-Activated K+ Channel MVP

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985891/pdf/bi4014243.pdf

Structural Mechanism of Voltage-Dependent Gating in an Isolated Voltage-Sensing Domain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116111/pdf/nihms606153.pdf

Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918809/pdf/pnas.201314875.pdf

Structural Basis of Lipid-Driven Conformational Transitions in the KvAP Voltage Sensing Domain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946318/pdf/nihms-540683.pdf

Recovery from Slow Inactivation in K+ Channels is Controlled by Water Molecules

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799803/pdf/nihms495778.pdf

Binding of the CYK-4 Subunit of the Centralspindlin Complex Induces a Large Scale Conformational Change in the Kinesin Subunit

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707682/pdf/zbc19785.pdf

Lucy Ann Godley

Treatment of Acute Promyelocytic Leukemia in Adults

http://ascopubs.org/doi/pdf/10.1200/JOP.18.00328

MBD4: guardian of the epigenetic galaxy

http://www.bloodjournal.org/content/bloodjournal/132/14/1468.full.pdf

Hereditary Myelodysplastic Syndrome and Acute Myeloid Leukemia: Diagnosis, Questions, and Controversies

https://link.springer.com/content/pdf/10.1007%2Fs11899-018-0473-7.pdf

Characterization of cancer comorbidity prior to allogeneic hematopoietic cell transplantation

https://www.tandfonline.com/doi/full/10.1080/10428194.2018.1493728#aHR0cHM6Ly93d3cudGFuZGZvbmxpbmUuY29tL2RvaS9wZGYvMTAuMTA4MC8xMDQyODE5NC4yMDE4LjE0OTM3Mjg/bmVlZEFjY2Vzcz10cnVlQEBAMA==

Microbial signals drive pre–leukaemic myeloproliferation in a Tet2–deficient host

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238954/pdf/nihms-990067.pdf

Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma

http://cancerres.aacrjournals.org/content/canres/78/10/2747.full.pdf

Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787862/pdf/advances013037.pdf

A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756334/pdf/13045_2017_Article_550.pdf

Reduced-Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared with Matched Unrelated Donor Stem Cells in Older Adults

https://reader.elsevier.com/reader/sd/pii/S1083879117318244?token=AB4AFDCC31FC70C13E83376FD8E0C4C4A145C1552B38696F30D18EC2BA3D411896C7E4C1BA561793106FF026B5260402

Clinical Assessment and Diagnosis of Germline Predisposition to Hematopoietic Malignancies: The University of Chicago Experience

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723667/pdf/fped-05-00252.pdf

Mutant RUNX1 and histone tales

http://www.bloodjournal.org/content/bloodjournal/130/20/2156.full.pdf

Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668941/pdf/1830.pdf

Therapy-Related Myeloid Neoplasms: When Genetics and Environment Collide

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946699/pdf/nihms963022.pdf

Recognition of familial myeloid neoplasia in adults

https://reader.elsevier.com/reader/sd/pii/S0037196316301202?token=18AAE3E407E1DB87B82EC9CE372BBA98421F116698CCFDFC2E5CC964584F4A82B59385E6895D46007E60ED960E58CF6C

Genetic predisposition to hematologic malignancies: management and surveillance

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533201/?report=printable

Germline ETV6 mutations and predisposition to hematological malignancies

https://link.springer.com/content/pdf/10.1007%2Fs12185-017-2259-4.pdf

DNAJC21: the new kid on the SDS block

http://www.bloodjournal.org/content/bloodjournal/129/11/1413.full.pdf

Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia

https://www.tandfonline.com/doi/full/10.1080/10428194.2017.1289524#aHR0cHM6Ly93d3cudGFuZGZvbmxpbmUuY29tL2RvaS9wZGYvMTAuMTA4MC8xMDQyODE5NC4yMDE3LjEyODk1MjQ/bmVlZEFjY2Vzcz10cnVlQEBAMA==

Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420790/pdf/leu201728a.pdf

Genetic predisposition to leukemia and other hematologic malignancies

https://ac.els-cdn.com/S0093775416300288/1-s2.0-S0093775416300288-main.pdf?_tid=0d11a0a3-2955-47e1-ae06-d3de08fc6f34&acdnat=1543251894_3253e70b0d0e49a8021f89556d88c3a4

Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340231/pdf/oncotarget-07-76816.pdf

Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592729/pdf/nihms902994.pdf

Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925265/pdf/nihms788919.pdf

Erratum to “5-hydroxymethylcytosine in cancer: Significance in diagnosis and therapy” [Cancer Genet 208 (2015):167–177]

https://ac.els-cdn.com/S****************/1-s2.0-S****************-main.pdf?_tid=b1500788-4421-4990-a7b6-b833d69a2f3b&acdnat=1543252037_189639ad260bb08ccd675435e5fcc6b2

Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial

https://ac.els-cdn.com/S1470204516000097/1-s2.0-S1470204516000097-main.pdf?_tid=8ce08231-db2b-4d74-948c-06edaf39d602&acdnat=1543252060_761fa682e7f72e96b3c11cd6fca26d6e

Frequency and Risk Factors Associated with Cord Graft Failure after Transplant with Single-Unit Umbilical Cord Cells Supplemented by Haploidentical Cells with Reduced-Intensity Conditioning

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867292/pdf/nihms767475.pdf

Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004373/pdf/1010634.pdf

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

http://www.bloodjournal.org/content/bloodjournal/127/12/1575.full.pdf

Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968341/?report=printable

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759199/pdf/zbc4256.pdf

Incidence and predictors of respiratory viral infections by multiplex PCR in allogeneic hematopoietic cell transplant recipients 50 years and older including geriatric assessment

https://www.tandfonline.com/doi/full/10.3109/10428194.2015.1113279#aHR0cHM6Ly93d3cudGFuZGZvbmxpbmUuY29tL2RvaS9wZGYvMTAuMzEwOS8xMDQyODE5NC4yMDE1LjExMTMyNzk/bmVlZEFjY2Vzcz10cnVlQEBAMA==

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722284/?report=printable

Inherited mutations in cancer susceptibility genes are common among breast cancer survivors who develop therapy-related leukemia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707981/pdf/nihms709851.pdf

TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668370/pdf/srep17568.pdf

Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661171/?report=printable

Correspondence Regarding the Consensus Statement from the Worldwide Network for Blood and Marrow Transplantation Standing Committee on Donor Issues

https://ac.els-cdn.com/S1083879115006783/1-s2.0-S1083879115006783-main.pdf?_tid=09b1bb52-43d0-422b-a01c-380430bc9237&acdnat=1543252464_e36e1acab49cedb1e2d2210596d81c8d

Epigenetic control of Apolipoprotein E expression mediates gender-specific hematopoietic regulation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713251/pdf/nihms725787.pdf

DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591215/pdf/nihms716536.pdf

Characterization of CpG sites that escape methylation on the inactive human X-chromosome

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622068/pdf/kepi-10-09-1069461.pdf

TET2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor binding sites in chronic myelomonocytic leukemia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506197/pdf/nihms691591.pdf

Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms

https://ac.els-cdn.com/S1535610815001051/1-s2.0-S1535610815001051-main.pdf?_tid=a78e4048-d0cc-4af2-b442-3aedcbecd3e3&acdnat=1543419314_02dbd76d0da84a0e07a081fcdb3e91da

5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy

https://ac.els-cdn.com/S2210776215000307/1-s2.0-S2210776215000307-main.pdf?_tid=47aad8d9-6de8-4cda-a07e-2526a5b9d0a0&acdnat=1543419340_0e2e87d2fb8c990b61c8fc779a313f3b

DNMT3B7 Expression Promotes Tumor Progression to a More Aggressive Phenotype in Breast Cancer Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301645/pdf/pone.0117310.pdf

Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540357/pdf/nihms687014.pdf

New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine

https://onlinelibrary.wiley.com/doi/epdf/10.1111/imr.12242

A Phase I and Pharmacodynamic Study of the Histone deacetylase inhibitor Belinostat plus Azacitidine in Advanced Myeloid Neoplasia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390421/pdf/nihms647416.pdf

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267494/pdf/nihms641392.pdf

Inherited Predisposition to Acute Myeloid Leukemia

https://ac.els-cdn.com/S0037196314000523/1-s2.0-S0037196314000523-main.pdf?_tid=4444dec4-67ef-4a0e-be8d-642314fad5b4&acdnat=1543419507_67e9a6aae56b58d2380befcca483662a

Hematopoietic stem-cell transplantation for advanced systemic mastocytosis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876356/pdf/zlj3264.pdf

Linking the genetic architecture of cytosine modifications with human complex traits

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204771/pdf/ddu313.pdf

The mechanistic role of DNA methylation in myeloid leukemogenesis

https://www.nature.com/articles/leu2014163.pdf

TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516227/pdf/nihms591957.pdf

Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116837/pdf/0991373.pdf

On the origin of leukemic species

https://ac.els-cdn.com/S1934590914001027/1-s2.0-S1934590914001027-main.pdf?_tid=bd3a8650-0efb-4df4-a216-e8a330c9d107&acdnat=1543420384_57672458483a801894ff0de3b2075e18

A new family with a germline ANKRD26 mutation and predisposition to myeloid malignancies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206674/pdf/nihms608400.pdf

The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013207/pdf/nihms571143.pdf

Familial myelodysplastic syndrome/acute leukemia syndromes: a review and utility for translational investigations

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961519/pdf/nihms548360.pdf

Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976649/pdf/nihms-552894.pdf

Large conserved domains of low DNA methylation maintained by Dnmt3a

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920905/pdf/nihms537224.pdf

Alterations of 5-hydroxymethylcytosine in human cancers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795365/pdf/cancers-05-00786.pdf

Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770813/pdf/nihms-496342.pdf

Recognizing familial myeloid leukemia in adults

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734901/pdf/10.1177_2040620713487399.pdf

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763560/pdf/gkt601.pdf

Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730924/pdf/987.pdf

Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies

https://ac.els-cdn.com/S003719631300005X/1-s2.0-S003719631300005X-main.pdf?_tid=8a1c31f1-1629-4fba-abad-b34660c067d7&acdnat=1543420699_7093cb6e432e5ef5460f21f496007ac8

Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596965/?report=printable

Pharmacogenomics of chemotherapeutic susceptibility and toxicity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580423/pdf/gm391.pdf

Immune reconstitution after combined haploidentical and umbilical cord blood transplant

https://www.tandfonline.com/doi/full/10.3109/10428194.2012.739688#aHR0cHM6Ly93d3cudGFuZGZvbmxpbmUuY29tL2RvaS9wZGYvMTAuMzEwOS8xMDQyODE5NC4yMDEyLjczOTY4OD9uZWVkQWNjZXNzPXRydWVAQEAw

A drug that stops traffic at the nuclear border

http://www.bloodjournal.org/content/bloodjournal/120/9/1759.full.pdf

Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445765/pdf/nihms396831.pdf

Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes

https://www.tandfonline.com/doi/full/10.3109/10428194.2012.701738#aHR0cHM6Ly93d3cudGFuZGZvbmxpbmUuY29tL2RvaS9wZGYvMTAuMzEwOS8xMDQyODE5NC4yMDEyLjcwMTczOD9uZWVkQWNjZXNzPXRydWVAQEAw

Jayasri Nanduri

Therapeutic Targeting of the Carotid Body for Treating Sleep Apnea in a Pre-clinical Mouse Model

https://link.springer.com/protocol/10.1007%2F978-1-4939-7665-2_14

Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia

https://link.springer.com/content/pdf/10.1007%2Fs00441-018-2807-0.pdf

DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity

https://physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/JP274833

Epigenetic changes by DNA methylation in chronic and intermittent hypoxia

https://www.physiology.org/doi/pdf/10.1152/ajplung.00325.2017

Complementary roles of gasotransmitters CO and H2S in sleep apnea

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307452/pdf/pnas.201620717.pdf

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505181/pdf/nihms869797.pdf

Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199741/pdf/TJP-595-63.pdf

Calpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865081/?report=printable

CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760493/?report=printable

Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872510/pdf/nihms783465.pdf

Epigenetic regulation of Carotid Body Oxygen Sensing: Clinical Implications

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870818/pdf/nihms786158.pdf

Protein kinase G–regulated production of H2S governs oxygen sensing

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418480/pdf/nihms684264.pdf

Peripheral chemoreception and arterial pressure responses to intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423746/pdf/nihms684256.pdf

Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409567/pdf/nihms672392.pdf

HIF-1α activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353619/pdf/pone.0119762.pdf

Neuromolecular mechanisms mediating the effects of chronic intermittent hypoxia on adrenal medulla

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373452/pdf/nihms-654960.pdf

Interleukin-12 preserves the cutaneous physical and immunological barrier after radiation exposure

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306454/pdf/nihms655645.pdf

An Arginine-Glycine-Rich RNA Binding Protein Impacts the Abundance of Specific mRNAs in the Mitochondria of Trypanosoma brucei

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311915/pdf/zek149.pdf

CaV3.2 T-type Ca²⁺ channels in H₂S-mediated hypoxic response of the carotid body

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297770/?report=printable

Regulation of hypoxia-inducible factor-α isoforms and redox state by carotid body neural activity in rats

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192707/pdf/tjp0592-3841.pdf

TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516227/pdf/nihms591957.pdf

Intermittent hypoxia-induced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989715/?report=printable

Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903201/pdf/pnas.201322172.pdf

Xanthine Oxidase Mediates Hypoxia-Inducible Factor-2α Degradation by Intermittent Hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790816/pdf/pone.0075838.pdf

Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808500/pdf/nihms514299.pdf

Impairment of pancreatic β-cell function by chronic intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756548/pdf/nihms486216.pdf

Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651442/pdf/pnas.201305961.pdf

Developmental programming of O(2) sensing by neonatal intermittent hypoxia via epigenetic mechanisms

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893877/pdf/nihms523777.pdf

Alfredo Garcia

Breaking down CO2: bicarbonate the other side of central chemosensitivity in retrotrapezoid nucleus neurons

https://physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/JP276558

Chronic Intermittent Hypoxia Differentially Impacts Different States of Inspiratory Activity at the Level of the preBötzinger Complex

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603985/pdf/fphys-08-00571.pdf

Different roles for inhibition in the rhythm-generating respiratory network

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626906/?report=printable

A novel excitatory network for the control of breathing

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479418/pdf/nihms868930.pdf

Chronic Intermittent Hypoxia Alters Local Respiratory Circuit Function at the Level of the preBötzinger Complex

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740384/pdf/fnins-10-00004.pdf

Prostaglandin E2 differentially modulates the central control of eupnoea, sighs and gasping in mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293069/pdf/tjp0593-0305.pdf

The ins and outs of breathing

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060004/pdf/elife03375.pdf

When Norepinephrine Becomes a Driver of Breathing Irregularities: How Intermittent Hypoxia Fundamentally Alters the Modulatory Response of the Respiratory Network

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866492/pdf/zns36.pdf

β-Noradrenergic receptor activation specifically modulates the generation of sighs in vivo and in vitro

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824105/pdf/fncir-07-00179.pdf

Central and peripheral factors contributing to obstructive sleep apneas

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901437/pdf/nihms516758.pdf

The physiological determinants of sudden infant death syndrome

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812300/pdf/nihms516954.pdf

Post-Hypoxic Recovery of Respiratory Rhythm Generation Is Gender Dependent

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620234/pdf/pone.0060695.pdf

Cardiorespiratory coupling in health and disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683976/pdf/nihms456314.pdf

Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623668/pdf/nihms451102.pdf

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652398/pdf/nihms459409.pdf

Ying-Jie Peng

Complementary roles of gasotransmitters CO and H2S in sleep apnea

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307452/pdf/pnas.201620717.pdf

Oxygen Sensing by the Carotid Body: Past and Present

https://link.springer.com/chapter/10.1007%2F978-3-319-55231-6_1

Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199741/pdf/TJP-595-63.pdf

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505181/pdf/nihms869797.pdf

CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760493/?report=printable

Protein kinase G-regulated production of H2S governs oxygen sensing

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418480/pdf/nihms684264.pdf

Peripheral chemoreception and arterial pressure responses to intermittent hypoxi

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423746/pdf/nihms684256.pdf

Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409567/pdf/nihms672392.pdf

Neuromolecular Mechanisms Mediating the Effects of Chronic Intermittent Hypoxia on Adrenal Medulla

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373452/pdf/nihms-654960.pdf

Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872510/pdf/nihms783465.pdf

CaV3.2 T-type Ca²⁺ channels in H₂S-mediated hypoxic response of the carotid body

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297770/?report=printable

Regulation of hypoxia-inducible factor-α isoforms and redox state by carotid body neural activity in rats

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192707/pdf/tjp0592-3841.pdf

Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903201/pdf/pnas.201322172.pdf

Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808500/pdf/nihms514299.pdf

Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651442/pdf/pnas.201305961.pdf

Protein kinase G-regulated production of H2S governs oxygen sensing

Reactivee oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia

Immunohistochemistry of the Carotid Body

The role of hypoxia-inducible factors in carotid body (patho) physiology

Measurement of Sensory Nerve Activity from the Carotid Body

DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity

Epigenetic changes by DNA methylation in chronic and intermittent hypoxia

Oxygen Sensing by the Carotid Body: Past and Present

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

Systems Biology of Oxygen Homeostasis

Complementary roles of gasotransmitters CO and H2S in sleep apnea

Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients